Obesity increases the risk of hypertension. Clinical studies confirm that the greater body weight, the higher blood pressure. And vice versa blood pressure decreases when reducing body weight. Blood pressure enhances the functions of sympathetic nervous system, which is able to change the kidneys structure and activity.
In obese patients, a risk of hypertension is 50% higher than in patients, whose body weight is normal. In excess weight, lipoprotein metabolism disorder occurs due to which:
Insulin resistance increases simultaneously with weight gain, but glycemic control is improved when reducing body weight. Thus, overweight is a risk factor of type 2 diabetes.
Hypertension and type 2 diabetes increase the risk of cardiovascular complications. Moreover, obesity accompanied with hypertension increases a risk of coronary heart disease by more than 2 times and stroke occurrence – by 7 times.
Hypertension may develop both in obesity arisen independently and in obesity arisen as a result of endocrine dysfunctions. Timely and proper treatment of endocrine disease can reduce overweight and normalize blood pressure.
Obesity treatment accompanied with hypertension
In modern clinical practice, reduction in body weight is the main purpose of hypertension therapy accompanied with obesity. Reduction in body weight just by 5-10% normalizes metabolic control, facilitates achievement of optimal blood pressure level and significantly reduces a risk of cardiovascular complications.
To treat obesity and to reduce the risk of associated diseases, it is recommended to take Duromine drug for weight loss. Patients with hypertension are recommended to take a minimum daily dosage of Duromine 15mg daily for weight loss.
Before to use Duromine together with hypotensive drugs, drug interactions should be carefully studied. Since Duromine possesses a property to reduce hypotensive effect of Clonidine, Methyldopa, Guanethidine medications, patients with high blood pressure may require increase in daily dose of these antihypertensive medications.
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